Molecular and Cellular Control of Humoral Immunity

 Saturday, May 7, 2022     10:15 AM – 12:15 PM ET     Room C123–124

Molecular and Cellular Control of Humoral Immunity

Chairs

• Wei Luo, Indiana Univ. Sch. of Med.
• Patricia Gearhart, NIA, NIH

Speakers

• Carlos J. Ticas Rodas, NIA, NIH, Follicular B cells from old mice are hyper-responsive and produce non-specific antibodies
• Christian Cervantes, Univ. of Texas Hlth. Sci. Ctr. San Antonio, PD-L1 plays a B cell-intrinsic role in suppressing the antibody response and anti-tumor immunity
• Wei Luo, Indiana Univ. – Sch. of Med., Blimp1 controls GC B cell expansion and exit through regulating cell cycle progression and key transcription factors BCL6 and IRF4
• Kim Good-Jacobson, Monash Univ., Targeting intrinsic regulators of antibody and B cell memory to control chronic viral infection
• William Voss, Univ. of Texas at Austin, Differential serological immune imprinting following SARS-CoV-2 infection, vaccination, and breakthrough infection
• Brian T. Gaudette, Perelman Sch. of Med., Univ. of Pennsylvania, The plasma cell proteome initiates early in B cell activation in advance of Blimp-1
• J. Scott Hale, Univ. of Utah Sch. of Med., Tet2-mediated programing balances T follicular helper cell and T helper 1 cell differentiation
• Nicole M. Arroyo, Univ. of Alabama at Birmingham, A temporal switch in T follicular helper cells controls the output of the GC response to influenza