Molecular, Metabolic, and Epigenetic Regulation of Innate Immunity and Inflammation

 Saturday, May 7, 2022     3:45 PM – 5:45 PM ET     Room A105–106

Molecular, Metabolic, and Epigenetic Regulation of Innate Immunity and Inflammation

Chairs

• Connie Krawczyk, Van Andel Inst.
• Sarah Ewald, Univ. of Virginia

Speakers

• Chao Yang, Hosp. for Special Surgery, Costimulation of TLR8 responses by CXCL4 in human monocytes mediated by TBK1-IRF5 signaling and epigenomic remodeling
• Matthew D. Woolard, Louisiana State Univ. Hlth. Sciences Ctr. at Shreveport, Lipin-1 integrates lipid metabolism with macrophage function to promote inflammation resolution
• David Orlando Diaz-Jimenez, NIEHS, NIH, Glucocorticoids suppress NLRP3 Inflammasome activation through transcriptional metabolic reprogramming of IRG-1/ACOD1 in macrophages
• Raza Ali Naqvi, Univ. of Illinois at Chicago, Modulation of myeloid cell functions by long noncoding RNAs RN7SK and HCG11
• Alicer Keendalyn Andrew, Univ. of Georgia, Relationships between inflammation, coagulation, and oxidative stress in malaria-induced pregnancy compromise
• Abhimanyu Abhimanyu, Baylor Col. of Med., Targeting TCA cycle metabolites by small molecule inhibitors ameliorate LPS induced immune tolerance in Macrophages through epigenetic mechanisms
• Katherine E. Lothstein, Rutgers Univ. New Jersey Med. Sch., Helminth TGF-β mimic, TGM, increases leukocyte migration and activation while also enhancing cutaneous wound healing and tissue regeneration