Innate Immune Sensing and Signaling

 Monday, May 9, 2022     12:30 PM – 2:30 PM ET     Room B117–119

Innate Immune Sensing and Signaling

Chairs

• Yuan He, Wayne State Univ. Sch. of Med.
• Jian Zhang, Univ. of Iowa

Speakers

• Yilei Ma, Univ. of Iowa, E-Syt1 ubiquitination by Nedd4 limits the caspase-11-mediated non-canonical inflammasome and endotoxemia
• Yuan He, Wayne State Univ., Molecular basis for NEK7-mediated NLRP3 inflammasome activation
• Chi Gidley Weindel, Texas A&M Univ., Col. of Med., Gasdermin D promotes hyperinflammation by triggering necroptosis in the presence of mitochondrial stress
• Swathy Ollikara Vasudevan, UConn Hlth., A TLR4-independent critical role for CD14 in intracellular LPS sensing
• Matthew R. Rice, Feinstein Inst. for Med. Res., STK25 functions as an IRF5 kinase to promote TLR7/8-mediated inflammation
• Nayeon Son, Missouri State Univ., Identification of a novel protein interactions that elucidates the mechanism of hydatidiform molar pregnancies in women with NLRP2 and NLRP7 mutations
• Jamie L. Shirley, Univ. of Colorado Anschutz Med. Campus, PD-L1 back signaling manipulates IL-6 signaling to coordinate innate immune responses