Tumor Microenvironment (TME) I

 Sunday, May 8, 2022     3:45 PM – 5:45 PM ET     Room B113–116

Tumor Microenvironment (TME) I

Chair

• Dorina Avram, H. Lee Moffitt Cancer Ctr. and Res. Inst.

Speakers

• Gunjan Mandal, H. Lee Moffitt Cancer Ctr. and Res. Inst., Spontaneous class-switched antibody responses at endometrial cancer tumor bed drives superior patients’ outcome
• Zihan Guo, Oregon Hlth. and Sci. Univ., Class switching is required for antigen-dependent b cell anti-tumor activity
• Zhi-Zhang Yang, Mayo Clin., T-cell phenotype varies in distinct tumor microenvironments and CD57⁺ T_FH cells are associated with disease progression and inferior survival in follicular lymphoma
• Juyeun Lee, Cleveland Clin. Fndn., Sex-specific T cell behavior drives differential immune responses in mouse glioblastoma models
• Stephanie Gomez, George Washington Univ., Inhibition of DNMTs and RNA editing increases immunogenic transposable element RNA to reduce tumor burden and prolong survival in a murine ovarian cancer model
• Tahereh Ziglari, Oregon Hlth. and Sci. Univ., Senescent cell-derived extracellular vesicles are critical elements in senescence surveillance by recruiting antigen-presenting cells
• Thejaswini Giridharan, Roswell Park Comprehensive Cancer Ctr., Role of the extracellular ATP/adenosine pathway in neutrophil-mediated T cell suppression in ovarian cancer microenvironment